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Oncology
Oncology

Congress Materials – European Society for Medical Oncology (ESMO 2024)

 

2024 European Society for Medical Oncology | Sep 13-17 | Barcelona, Spain

This section includes selected Johnson & Johnson Innovative Medicine abstracts, posters, or oral presentations, which have been accepted for congress presentations in the last 2 years or less (as determined by any congress restrictions on length of time materials can be posted). Information about pipeline products or investigational uses of products does not imply FDA approval for these products or uses, nor does it establish the safety or efficacy of these products or uses.  Johnson & Johnson does not recommend or suggest use of its medicines in a manner inconsistent with FDA-approved labeling. The content contained in this section is subject to congress copyright permissions.

 

A Deep Learning Approach Using Routine Pathology Images to Guide Precision Medicine in Metastatic CRC

Chaitanya Parmar, Albert Juan Ramon, Patricia Raciti, Kris Standish, Sanjib Chowdhury, Supriya Shah, Fernando Cruz-Guilloty, Joshua C. Curtin, Mahadi Baig, Robert Schnepp, Xuesong Lyu, Zayed Albertyn, Chris Moy, Joel Greshock, Lev Demirdjian

 

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A Phase 1, First-in-Human, Open-Label, Multicenter, Trial-in-Progress of the Safety, Tolerability, and Preliminary Efficacy of JNJ-87189401 (PSMA-CD28 Bispecific Antibody) Combined With JNJ-78278343 (KLK2-CD3 Bispecific Antibody) for Advanced Prostate Cancer

Mark N. Stein, Laura S. Graham, Capucine Baldini, Armelle Vinceneux, Elizabeth R. Kessler, Karie Runcie, Alexander Z. Wei, Kyriakos Papadopolous, Alice Bernard-Tessier, Marie Laurent, Pharavee Jaiprasart, Daksh Thaper, Fei Shen, Leanne Cartee, Edward Attiyeh, Victor Villalobos, Drew W. Rasco

 

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Amivantamab Plus Chemotherapy vs Chemotherapy in EGFR-mutated, Advanced Non-small Cell Lung Cancer After Disease Progression on Osimertinib: 2nd Interim Overall Survival From MARIPOSA-2

Sanjay Popat, Karen L. Reckamp, Raffaele Califano, Se-Hoon Lee, Barbara Melosky, Jie Wang, Yongsheng Wang, Maria del Rosario Garcia Campelo, Enriqueta Felip, Nicolas Girard, Ryan D. Gentzler, William Nassib William Jr, Toshiaki Takahashi, Misako Nagasaka, Joshua M. Bauml, Sujay Shah, Brooke Diorio, Pei-Ling Chu, Byoung Chul Cho, Antonio Passaro

 

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Amivantamab Plus FOLFOX or FOLFIRI in Metastatic Colorectal Cancer: Results From OrigAMI-1, a Phase 1b/2 Study

Filippo Pietrantonio, Gwo Fuang Ho, Yu-Li Su, Eric Xueyu Chen, Ying Yuan, Pei Jye Voon, Xinjun Liang, Derek Jonker, Federico Longo, J. Randolph Hecht, Sreenivasa Chandana, Dirk Arnold, Rianka Bhattacharya, Joshua C. Curtin, Scott Maul, Ryota Iwasawa, Sanjib Chowdhury, Robert W. Schnepp, Mahadi Baig, Yong Sang Hong

 

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Association of PD-L1 Expression With Clinical Response to TAR-200 in the Phase 2b SunRISe-1 Trial

Evanguelos Xylinas, Christopher M. Pieczonka, Joseph M. Jacob, Andrea Necchi, Siamak Daneshmand, Giuseppe Simone, Karel Decaestecker, Girish S. Kulkarni, Martin Bögemann, Félix Guerrero Ramos, Justin Callaway, Neil Beeharry, Jiarui Zhang, Shalaka Hampras, Hussein Sweiti, Katharine Stromberg, Jason Martin, Abhijit Shukla, Patricia Raciti, Michiel S. van der Heijden

 

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Clinical Validity of Plasma DNA Testing to Identify BRCA-mutated (BRCA+) Patients in the MAGNITUDE Study

Gerhardt Attard, Usha Singh, Yaji Xu, Lesley Farrington, Katherine Bell, Karen Urtishak, Won Kim, Jenny Zhang, Sarah Parsons, Kate (Yueyi) Li, Melissa Schwenk, Wei Li, Songbai Wang

 

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Impact of FANCA, ATM, CDK12 Alterations on Survival in Metastatic Castration-Resistant Prostate Cancer (mCRPC)

David Lorente, Bernardo Herrera Imbroda, Ana Jambrina, Daniiel Tello, Nuria Romero-Laorden, Pedro Lopez Casas, Manuel Balongo, Maria Ovejero, Laura Almalé, Natalia Vidal Cassinello, Maria J. Méndez-Vidal, Camille Capone, Anne M. Vanden Broecke, Marco Trevisan, Suzy Van Sanden, Alexandra Jürgens, Enrique Gonzalez-Billalabeitia, David Olmos, Elena Castro

 

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Mechanisms of Acquired Resistance to First-Line Amivantamab Plus Lazertinib Versus Osimertinib in Patients With EGFR-Mutant Advanced Non-Small Cell Lung Cancer: An Analysis From the Phase 3 MARIPOSA Study

Benjamin Besse, Se-Hoon Lee, Shun Lu, Daniil Stroyakovsky, Ozan Yazici, Igor Bondarenko, Jeronimo Rafael Rodriguez, Hidetoshi Hayashi, Danny Nguyen, James Chih-Hsin Yang, Maya Gottfried, Ana Caroline Zimmer Gelatti, Scott Owen, Sai-Hong Ignatius Ou, Mariah Ennis, Seema Sethi, Joshua M. Bauml, Jiarui Zhang, Joshua C. Curtin, Byoung Chul Cho

 

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Preventing Infusion-Related Reactions With Intravenous Amivantamab: Updated Results From SKIPPirr, a Phase 2 Study

Luis Paz-Ares, Alexander I. Spira, Ji-Youn Han, Jin-Yuan Shih, Céline Mascaux, Upal Basu Roy, Jon Zugazagoitia, Yu Jung Kim, Chao-Hua Chiu, Sang-We Kim, Ernest Nadal, Ignacio Gil-Bazo, Sean Murphy, Parthiv Mahadevia, Bailey G. Anderson, Karen Xia, George Wang, Joshua M. Bauml, Marc Chioda, Jairo Simoes, Gilberto Lopes

 

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TAR-200 +/- Cetrelimab and Cetrelimab Alone in Patients With Bacillus Calmette Guérin–Unresponsive High-Risk Non–Muscle-Invasive Bladder Cancer: Updated Results From SunRISe-1

Michiel S. van der Heijden, Giuseppe Simone, Martin Bögemann, Evanguelos Xylinas, Mathieu Roumiguié, Felix Guerrero-Ramos, Andrea Necchi, Siamak Daneshmand, Charles Van Praet, Philipp Spiegelhalder, Karel Decaestecker, Harm Arentsen, Daniel Zainfeld, Shalaka Hampras, Christopher J. Cutie, Hussein Sweiti, Katharine Stromberg, Jason Martin, Abhijit Shukla, Joseph M. Jacob

 

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TAR-200 Plus Cetrelimab or Cetrelimab Alone as Neoadjuvant Therapy in Patients With Muscle-Invasive Bladder Cancer Who Are Ineligible for or Refuse Neoadjuvant Cisplatin-Based Chemotherapy: Interim Analysis of SunRISe-4

Andrea Necchi, Felix Guerrero-Ramos, Paul L. Crispen, Bernardo Herrera-Imbroda, Rohan Garje, Thomas Powles, Charles C. Peyton, Benjamin Pradere, Ja Hyeon Ku, Neal Shore, Martin Bögemann, Mark A. Preston, Evanguelos Xylinas, Cinty Gong, Saltanat Najmi, Mohamad Hasan, Hind Stitou, Sumeet Bhanvadia, Hussein Sweiti, Sarah P. Psutka

 

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Urine-Based Molecular Testing Identifies FGFR Alteration-Positive Patients for Treatment With TAR-210

Felix Guerrero-Ramos, Ja Hyeon Ku, Antoni Vilaseca Cabo, Carles Raventós, Neal Shore, Josh Meeks, Roger Li, Siamak Daneshmand, Gautam Jayram, Taek Won Kang, Neil Beeharry, Jiarui Zhang, David Weingeist, Denis Smirnov, Bethany Brunton, Carrye Cost, Anna Kalota, Josh Lauring, Nicole Stone, Shibu Thomas

 

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Copies of these presentations are for personal use only and may not be reproduced without written permission from the presentation author.