Adult Schizophrenia

• Chouinard G,  Jones B, Remington G. A Canadian multicenter placebo-controlled study of fixed doses of risperidone and haloperidol in the treatment of chronic schizophrenic patients. J Clin Psychopharmacol. 1993;13(1):25-40.
• Marder SR, Meibach RC. Risperidone in the treatment of schizophrenia. Am J Psychiatry. 1994;151(6):825-835.
• Marder SR, Davis JM, Chouinard G. The effects of risperidone on the five dimensions of schizophrenia derived by factor analysis: combined results of the North American trials. J Clin Psychiatry. 1997;58:538-546.   
• Peuskens J. Risperidone in the treatment of patients with chronic schizophrenia: a multi-national, multi-centre, double-blind, parallel-group study versus haloperidol. Br J Psychiatry. 1995;166:712-726. 
• Csernansky JG, Mahmoud R, Brenner R, the USA-790 Study group. A comparison of risperidone and haloperidol for the prevention of relapse in patients with schizophrenia.  New Eng J Med. 2002(1)16-22.

Adolescent Schizophrenia Trials

• Haas M, Unis AS, Armenteros J. A 6-week, randomized, double-blind, placebo-controlled study of the efficacy and safety of risperidone in adolescents with schizophrenia. J Child Adolesc Psychopharmacol. 2009;19(6):611-621. 
• Haas M, Eerdekens M, Kushner S. Efficacy, safety, and tolerability of two risperidone dosing regimens in adolescent schizophrenia: double-blind study. Brit J Psychiatry. 2009;194(2):158-164.

Bipolar Disorder Monotherapy - Adult

• Hirschfeld R, Keck P, Kramer M. Rapid antimanic effect of risperidone monotherapy: A 3 week multicenter, double-blind, placebo-controlled trial. Am J Psychiatry. 2004; 161:1057-1065.
• Khanna S, Vieta E, Lyons B. Risperidone in the treatment of acute mania. Br J Psychiatry. 2005; 187:229-234.

Bipolar Mania-Adjunctive Therapy with Lithium or Valproate - Adult

• Sachs GS, Grossman F, Ghaemi SN. Combination of a mood stabilizer with risperidone or haloperidol for treatment of acute mania: a double-blind, placebo-controlled comparison of efficacy and safety. Am J Psychiatry. 2002;159:1146-1154.
• Yatham LN, Grossman F, Augustyns I. Mood stabilizers plus risperidone or placebo in the treatment of acute mania. Br J Psychiatry. 2003; 182:141-147.

Bipolar Disorder in Children and Adolescents

• Haas M,  DelBello MP,  Pandina G, et al. Risperidone for the treatment of acute mania in children and adolescents with bipolar disorder: a randomized, double-blind, placebo-controlled study. Bipolar Disord. 2009;11:687-700.

Irritability Associated with Autistic Disorder

• McCracken JT,  McGough J,  Bhavik S, et al. Risperidone in children with autism and serious behavioral problems. N Eng J Med. 2002;347:314-321.
• Pandina GJ,  Bossie CA,  Youssef E, et al. Risperidone improves behavioral symptoms in children with autism in a randomized, double-blind, placebo-controlled trial. J Autism Dev Disord. 2007;37:367-373.
• Kent JM,  Kushner S,  Ning X, et al. Risperidone dosing in children and adolescents with autistic disorder: a double-blind, placebo-controlled study. J Autism Dev Disord. 2013;43(8):1773-1783.
• Aman MG,  Arnold LE,  McDougle CJ, et al. Acute and long-term safety and tolerability of risperidone in children with autism. J Child Adolesc Psychopharmacol. 2005;15(6):869-884.